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Visfatin Exhibits Effects on Telomerase Gene Expression in AGS Cells

In the following study, researchers examine visfatin expression and its effect on telomerase gene expression in AGS cells. Reverse transcription polymerase chain reaction (RT-PCR) and enzyme-linked immunosobent assay were performed to analyze visfatin expression in mRNA and protein level. Total RNA was extracted and complementary deoxyribonucleic acid was synthesized to analyze telomerase gene expression. Results show that visfatin induces AGS cell proliferation and increases telomerase (hTERT) gene expression, which suggest that expression of visfatin in real protein in real samples could be a biomarker for gastric cancer. [LINK]


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