The AGS cell line originated in 1979 from the stomach tissue of a 54-year-old Caucasian female who had been diagnosed with gastric adenocarcinoma. AGS cells are tumorigenic, hyperdiploid, and have a modal chromosome number of 49. AGS exhibits adherent cultural properties and has an epithelial morphology. The AGS cell line is a good host for the study of stomach cancer and other stomach infections using in vivo and in vitro transfection methods. An AGS Transfection Reagent to transfect AGS cells is commercially available from Altogen Biosystems , and an AGS xenograft murine model is displayed here .